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Health

Sex Is a Natural Antidepressant: 1–2 Times a Week Cuts Depression Risk, Study Finds

Published in the Journal of Affective Disorders: Weekly intimacy triggers oxytocin and prolactin release while suppressing cortisol to regulate mood and emotional resilience.

Mental Health Desk

September 10, 2026• 4 min read

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Sex Is a Natural Antidepressant: 1–2 Times a Week Cuts Depression Risk, Study Finds - Greenline News

London: A landmark study published in the Journal of Affective Disorders found that an optimal sexual frequency of 1–2 times per week significantly mitigates depression risk in young and middle-aged adults.

Intimacy triggers the release of oxytocin and prolactin while sharply reducing cortisol, the body's primary stress hormone. The clinical pathway is clearly defined: Sexual intimacy → Restorative sleep → Mood regulation → Diminished depression odds.